Cocaine

Cocaine is an alkaloid found in leaves of the South American shrub Erythroxylon coca. It is a powerfully reinforcing psychostimulant. The drug induces a sense of exhilaration in the user primarily by blocking the reuptake of the neurotransmitter dopamine in the midbrain. If the predictions of The Hedonistic Imperative are vindicated, then future millennia will witness what Robert Anton Wilson once called "hedonic engineering". Mature enhancements of currently drug-induced states of euphoria will be transformed …

…very-mechanism oneself. This is at best very imprudent. Ultimately, the emotional baseline, and affective analogue of Absolute Zero, characteristic of post-humanity in its hedonically enriched modes of awareness may be greater than anything we can now grasp. It may be higher than the rapturous transports of the most euphoric coke-binge in paleo-human history. In the meantime, a drug which induces a secular parody of Heaven commonly leads the user into a biological counterpart of Hell.