Drug dissolution from an immediate release vs. modified release preparation of ibuprofen.

1. Introduction. Oral administration of analgesics for pain management is often the most convenient, safe, and effective means of delivery. For example, analgesics with a well established therapeutic effectiveness and safety profile, such as morphine, are widely employed in orally administered modified release forms in the management of chronic pain. Increasingly, chronic pain management is a therapeutic category in which controlled release provides the most desirable dosing regimens with desirable pharmacokinetic profile and pharmacodynamic response. This …

…we have none for comparison. If errors have occurred this may be due to inaccuracies in UV spec reading, and or sample taking, and may but most unlikely problems with our drugs themselves References. - M.E. Aulton, 2002, Pharmaceutics, second edition, Churchill livingstone. -Prof F. Podczech, 2004, MPH305 module guide - www.nurofen.co.uk / www.crookeshealthcare.com - copyright the Boots Company Limited, 2004 -Formulation Technology: Emulsions, Suspensions, Solid Forms Hans Mollet , Arnold Grubenmann Helen Payne, 2001