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Mutation in gene Unc-93 results in apparent muscle defects in C. Elegans.

Date Submitted: 06/02/2001 16:44:26
Length: 9 pages (2590 words)
Views: 191832

Mutation in gene Unc-93 results in apparent muscle defects in C. Elegans. John Mathew Joshua Kistner Dr. Lyczak November 8, 2002 Abstract Mutations occur when the base pairs in DNA are altered, and could result in everything from a minor change in phenotype to a lethal change in the cell. Unc-93 in Caenorhabditis elegans is responsible for muscle contraction. DNA strains from three worms: LU-55, LU-57, and N2 are extracted, purified, and analyzed to find out if …

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… 135, 53-70. 2.Levin, J.Z., and Horovitz, H.R. (1993). The Caenorhabditis elegans unc-93 gene encodes a putative transmembrane protein that regulates muscle contraction. J Cell Biology 117, 143-155. 3.Kohn, R., and Lyczak R. (2002). Genetics Laboratory Exercises, Ursinus College, Collegeville, PA. 4.Russell, Peter J. Genetics. San Francisco: Benjamin Cummings, 2002. 5.Shah A.A., Giddings M.C., Parvaz J.B., Gesteland R.F., Atkins J.F., Ivanov I.P. (2002). Computational identification of putative programmed translational frameshift sites. Bioinformatics 18, 1046-53.

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