Review of Evidence that the gene encoding ZDHHC8 contributes to the risk of schizophrenia. Mukai, J et al. Proc. Natl. Acad. Sci. USA

BACKGROUND: The brain and nervous system is very complicated the knowledge of how it works and functions to make animals think, behave and act is growing. Schizophrenia is a chronic and disabling psychosis - a disorder of thought and sense of self that affects the brain and nervous system. Patients may suffer from impairment of cognitive function, but schizophrenia is distinguished from other dementias where cognitive disturbance is primary. Numerous different genetic susceptibility points for …

…Sex differences in the risk of schizophrenia: evidence from meta-analysis. Arch. Gen. Psychiatry 60, 565-571 (2003). 7. Schwab et al. Support for association of schizophrenia with genetic variation in the 6p22.3 gene, dysbindin, in sib-pair families with linkage and in an additional sample of triad families. Am. J. Hum. Genet. 72, 2003. 185-190. 8. SOURCE. The University of Chicago. 2000. http://genome-www5.stanford.edu/cgi-bin/source/sourceResult?option=Number&criteria=BC009442&choice=Gene <Tab/>